Comparative Pharmacokinetics of Gallic Acid After Oral Administration of Gallic Acid Monohydrate in Normal and Isoproterenol-Induced Myocardial Infarcted Rats
نویسندگان
چکیده
Citation: Yu Z, Song F, Jin Y-C, Zhang W-M, Zhang Y, Liu E-J, Zhou D, Bi L-L, Yang Q, Li H, Zhang B-L and Wang S-W (2018) Comparative Pharmacokinetics of Gallic Acid After Oral Administration of Gallic Acid Monohydrate in Normal and Isoproterenol-Induced Myocardial Infarcted Rats. Front. Pharmacol. 9:328. doi: 10.3389/fphar.2018.00328 Comparative Pharmacokinetics of Gallic Acid After Oral Administration of Gallic Acid Monohydrate in Normal and Isoproterenol-Induced Myocardial Infarcted Rats
منابع مشابه
The effects of gallic acid on pain and memory following transient global ischemia/reperfusion in Wistar rats
Objective: It is generally agreed that most of the phenomena observed during brain ischemia and reperfusion can be explained by the damage to membrane structure. Oxidative stress is resulted in an imbalance between high consumption of oxygen and low levels of endogenous antioxidants. It is known that gallic acid (GA) is a strong antioxidant. The present study was carried out to evaluate the eff...
متن کاملGallic acid and exercise training improve motor function, nerve conduction velocity but not pain sense reflex after experimental sciatic nerve crush in male rats
Objective: The aim of present study was to evaluate the effects of oral administration of gallic acid (GA) for 21 days alone and in combination with exercise on nerve conduction velocity and sensory and motor functions in rats with sciatic nerve crush. Materials and Methods: Seventy adult male Wistar rats (250-300 g) were divided randomly into 7 groups with 10 in each: 1) Control (Cont), 2) Cru...
متن کاملThe anti-inflammatory and anti-apoptotic effects of gallic acid against mucosal inflammation- and erosions-induced by gastric ischemia-reperfusion in rats
The present study aimed to evaluate the protective effect of gallic acid on gastric mucosal lesions caused by ischemia-reperfusion (I/R) injury in rat. Forty male rats were randomly divided into sham, control (I/R injury) and three gallic acid-pretreated groups. To induce I/R lesions, the celiac artery was clamped for 30 min and then the clamp was removed to allow reperfusion for 6 hr. Pretreat...
متن کاملاسید گالیک حافظه و درد را در موش های صحرایی نر دیابتی بهبود میبخشد
Background: Complications of diabetes can be caused by the production of free radicals, which lead to memory problems and increase the risk of dementia. Diabetics are at risk of nervous pains. Gallic acid has antioxidant properties and activity against free radicals. In this study the effect of oral administration of Gallic acid, were examined on passive avoidance memory and pain in diabeti...
متن کاملEvaluation the Protective Role of Gallic Acid on Cardiac Arrhythmias Induced by Oxidative Stress in Rat Exposure to Particulate Matters
Introduction: Particulate matter (PM) increases the risk of heart disorders. Gallic acid (GA) with strong antioxidant properties has shown an effective role in reducing the complications of various diseases. The aim of this study was to evaluate the protective effect of Gallic acid in preventing cardiac arrhythmias due to exposure to particulate matter. Methods: In this study, 40 rats were pla...
متن کامل